Can Circadian Misalignment Influence Drug Efficacy?
Yes, circadian misalignment can significantly influence drug efficacy. The timing of drug administration can affect the therapeutic outcomes due to the circadian regulation of drug targets, absorption, distribution, metabolism, and excretion. Chronotherapy, which involves administering medications at specific times to align with the body's circadian rhythms, is an emerging field aimed at maximizing drug efficacy and minimizing side effects.
