Yes, cells have evolved mechanisms to repair damage to deoxyguanosine. The base excision repair (BER) pathway is primarily responsible for correcting oxidative lesions like 8-oxo-deoxyguanosine. Enzymes such as 8-oxoguanine glycosylase (OGG1) recognize and excise the damaged base, allowing for its replacement with an undamaged nucleotide. Efficient repair is essential to maintain genomic integrity and prevent the accumulation of mutations.
