Can ER Stress Be a Therapeutic Target in Toxicology?
Given its role in cellular homeostasis and response to toxic insults, ER stress is a potential therapeutic target. Modulating the UPR pathways to enhance cell survival or promote apoptosis in damaged cells is an area of ongoing research. Small molecules that can alleviate ER stress, like chemical chaperones, are being explored for their potential to treat diseases associated with toxic exposure and ER dysfunction.
