While lipoic acid is generally considered safe, excessive doses can lead to toxicity. Symptoms of lipoic acid toxicity may include gastrointestinal distress, such as nausea and diarrhea, as well as more severe effects like hypoglycemia, especially in individuals with diabetes. It is crucial to adhere to recommended doses, as high doses could potentially disrupt the balance of redox systems in the body, leading to oxidative stress rather than preventing it.