Yes, overnutrition, characterized by an excess intake of calories and nutrients, can influence toxicity. Obesity, a common outcome of overnutrition, has been linked to altered distribution and storage of lipophilic toxicants due to increased body fat. Moreover, conditions associated with obesity, such as non-alcoholic fatty liver disease, can impair the liver's ability to metabolize and detoxify chemicals. This can increase the risk of adverse effects from exposure to environmental contaminants.
