Can Proteostasis Regulators Mitigate Toxic Effects?
Yes, proteostasis regulators have the potential to mitigate the toxic effects of various substances. By enhancing the activity of chaperones, proteasomes, and autophagy pathways, these regulators can help maintain protein balance and prevent the accumulation of toxic protein aggregates. For example, small molecules that boost chaperone activity have shown promise in reducing toxicity in models of neurodegenerative diseases.
