Can These Pathways Be Targeted to Mitigate Toxicity?
Yes, targeting these pathways is a promising approach to mitigating toxicity. For example, antioxidants can be used to combat oxidative stress, potentially preventing the activation of the intrinsic pathway. Inhibitors of caspases or death receptor antagonists can also be used to block apoptotic signaling, providing a therapeutic approach to reducing cell death induced by toxicants.
