Carcinogenicity studies often involve long-term testing, usually spanning the lifetime of the test animals, which are typically rodents like mice and rats. The process includes:
1. Selection of Test Substance: Choosing the chemical or substance to be tested. 2. Dosing: Administering the substance in varying doses to different groups of animals. 3. Observation and Monitoring: Regularly observing the animals for any signs of [tumor] development or other health effects. 4. Histopathological Examination: Post-mortem examination of tissues to identify any microscopic changes indicative of cancer.
