How are Controls Selected for Toxicology Experiments?
The selection of appropriate controls depends on the specific goals and design of the experiment. Key factors include:
Purpose of the Study: The nature of the experiment will dictate whether negative, positive, or both types of controls are needed. Test Substance Characteristics: The properties of the test substance, such as its solubility and stability, will influence the choice of vehicle controls. Study Environment: Environmental controls are selected based on the conditions under which the experiment is conducted, to ensure these do not influence the outcomes.