How Are Enzymatic Functions Studied in Toxicology?
Researchers use various experimental models to study enzymatic functions in toxicology. In vitro experiments with isolated enzymes or cultured cells allow for detailed mechanistic studies, while in vivo studies in animals help understand systemic effects. Human studies, including pharmacogenomic research, provide insights into how genetic variations affect enzyme activity and toxicity. Advanced techniques like mass spectrometry and molecular docking are used to elucidate enzyme-substrate interactions and metabolic pathways.