How is PARP involved in the body's response to environmental toxins?
Environmental toxins, such as those found in cigarette smoke or industrial pollutants, can cause oxidative DNA damage, triggering PARP activation. The role of PARP in responding to such damage is a key area of study, as it helps determine the homeostatic balance between repair and cell death. Investigating PARPâs response to environmental toxins aids in understanding the mechanisms of toxicity and the development of potential interventions to mitigate damage.
