What Are the Implications of Enzyme Inhibition in Toxicology?
Enzyme inhibition can have significant toxicological implications. When enzymes are inhibited, the metabolism of certain compounds is reduced, leading to the accumulation of toxic substances or active drug forms. This is particularly relevant in drug interactions, where one drug inhibits the enzyme responsible for metabolizing another, potentially causing toxicity. Understanding enzyme inhibition is crucial for predicting and preventing adverse drug reactions.
