What Factors Affect Enzymatic Activity in Toxicology?
Several factors can impact enzymatic activity, including genetic polymorphisms, age, sex, diet, and exposure to other chemicals. Genetic polymorphisms in enzymes like cytochrome P450 can lead to differences in how individuals metabolize drugs and toxins, affecting their toxicity and efficacy. Age and sex can also influence enzyme expression and activity, as can diet and nutritional status. Additionally, exposure to certain chemicals can induce or inhibit enzyme activity, altering the metabolism of other compounds.
