How Are Transport Proteins Targeted in Toxicology Research?
Toxicology research often targets transport proteins to develop strategies for mitigating toxicity and enhancing therapeutic outcomes. For example, researchers are investigating the use of transport inhibitors to increase the intracellular concentration of chemotherapeutic agents in cancer cells, thereby overcoming drug resistance. Additionally, understanding the transport mechanisms of toxicants can aid in developing biomarkers for exposure and effect, as well as in designing safer chemicals.
