What Types of Transport Proteins Are Involved in Toxicology?
There are several types of transport proteins involved in toxicology, primarily categorized into ATP-binding cassette (ABC) transporters and solute carrier (SLC) transporters. ABC transporters, such as P-gp and multidrug resistance-associated proteins (MRPs), typically function as efflux pumps that remove toxins from cells. On the other hand, SLC transporters, like organic anion transporters (OATs) and organic cation transporters (OCTs), often facilitate the uptake of various substances, including drugs and toxicants, into cells.
