What role do PDEs play in drug development and safety?
In the context of drug development, PDEs are a significant target for novel therapeutic agents. Understanding their role in cellular signaling pathways aids in the design of drugs with specific actions and minimal side effects. From a safety perspective, evaluating the impact of PDE modulation on Clinical Trials is essential to predict potential toxicological risks. This involves examining PDE-related biomarkers and their changes in response to drug exposure.
