Studying receptor activation in toxicology involves a combination of in vitro, in vivo, and in silico approaches. In vitro assays use cell cultures to observe receptor-ligand interactions and downstream effects. In vivo studies employ animal models to understand the physiological relevance of receptor activation. Computational methods, like molecular docking and quantitative structure-activity relationship (QSAR) models, predict how chemicals might interact with receptors at the molecular level.
