How Can We Assess the Impact of Toxicants on the Non-Canonical Wnt Pathway?
To assess the impact of toxicants on the non-canonical Wnt pathway, researchers use a variety of biomarkers and experimental models. These include in vitro cell culture systems, in vivo animal models, and advanced techniques like CRISPR/Cas9 gene editing. By analyzing changes in gene expression, protein levels, and cellular behaviors, scientists can determine how toxicants affect Wnt signaling.
