What are the Implications of Disrupted Wnt Signaling in Toxicology?
Disruption of the non-canonical Wnt pathway can have significant implications in toxicology. For instance, it can contribute to carcinogenesis by affecting cell proliferation and apoptosis. Additionally, it can lead to developmental toxicity, as the pathway is vital for proper embryonic development. Understanding these disruptions can help in assessing the risk posed by various toxicants.
