What is the Role of the Non-Canonical Wnt Pathway?
Unlike the canonical Wnt pathway, which primarily regulates gene transcription through β-catenin, the non-canonical pathway is involved in cytoskeletal rearrangements and cell polarity. It is subdivided into the planar cell polarity (PCP) pathway and the Wnt/Ca2+ pathway. These pathways are crucial for processes such as cell migration, embryonic development, and organogenesis.
