ADIs are often compared to other safety measures such as the Reference Dose (RfD) used by the U.S. Environmental Protection Agency (EPA). Both measures are similar in concept but differ in application; ADIs are primarily used for food additives and residues, while RfDs are used for environmental chemicals. Another related measure is the Tolerable Daily Intake (TDI), which is used for contaminants that are not intentionally added to food but may be present due to environmental pollution.
