Endocrine disruptors can interfere with hormone actions in several ways. They may mimic natural hormones like estrogens and androgens, binding to their receptors and activating them. Alternatively, they can block these receptors, preventing natural hormones from binding and exerting their effects. Some disruptors may also interfere with the synthesis, transport, metabolism, or elimination of natural hormones, altering the concentrations of these hormones in the body.