How Do Environmental Toxins Affect the Dopaminergic System?
Environmental toxins, including pesticides like rotenone and paraquat, have been implicated in dopaminergic neuron damage. These chemicals can induce oxidative stress, mitochondrial dysfunction, and inflammation, leading to neuron death and increased risk of neurodegenerative diseases. Studies also suggest that prolonged exposure to heavy metals such as lead and manganese can disrupt dopamine synthesis and release, further affecting the system.
