Genetics play a significant role in an individual's susceptibility to cancer. Certain genetic mutations can increase the risk of cancer by altering the body's ability to process carcinogens or repair DNA damage. Toxicologists study genetic variations that affect metabolic pathways, such as those involving cytochrome P450 enzymes, which can influence the activation or detoxification of carcinogens. Knowledge of these genetic factors can inform personalized medicine approaches in oncology, allowing for tailored prevention and treatment strategies based on an individualâs genetic makeup.
