Hybrid techniques work by combining the principles and strengths of different analytical methods. For example, Liquid Chromatography-Mass Spectrometry (LC-MS) is a hybrid technique that couples the separation capabilities of liquid chromatography with the detection power of mass spectrometry. This combination allows for the separation of complex mixtures and the identification of compounds based on their mass-to-charge ratio. Similarly, Gas Chromatography-Mass Spectrometry (GC-MS) integrates gas chromatography with mass spectrometry to analyze volatile and semi-volatile compounds.
