How do Nucleotides relate to DNA Damage and Repair?
One of the primary concerns in toxicology is DNA damage caused by exposure to toxic substances, such as carcinogens, radiation, and oxidative stress. Nucleotides play a critical role in DNA repair processes, such as nucleotide excision repair and base excision repair. These repair mechanisms recognize and remove damaged nucleotides and replace them with correct ones, maintaining genomic stability and preventing mutations that could lead to cancer or other diseases.