Nucleotide imbalances can have significant toxicological implications. An excess or deficiency of specific nucleotides can disrupt DNA and RNA synthesis, leading to genomic instability and impaired cellular function. Additionally, nucleotide imbalances may affect the fidelity of DNA replication and repair, potentially leading to increased mutation rates and susceptibility to diseases. Understanding these imbalances is crucial for assessing the toxicological impact of various substances and developing strategies to mitigate their effects.
