The interaction of phospholipids with toxicants is a critical aspect of their role in toxicology. Toxicants can disrupt the phospholipid bilayer, altering membrane integrity and function. For instance, oxidative stress can lead to the peroxidation of phospholipids, compromising cell membrane stability. Lipophilic toxicants, such as certain drugs and environmental pollutants, can integrate into the lipid bilayer, affecting membrane fluidity and permeability.
