Yes, phospholipids can act as detoxifying agents. They participate in the sequestration and transport of toxic substances. Certain phospholipids can bind to toxicants, facilitating their removal from cells. The liver, for instance, uses phospholipids in the formation of bile, which helps in excreting lipophilic toxins. Moreover, phospholipids are involved in the formation of lipoproteins that transport hydrophobic molecules through the bloodstream.