What is the Role of Phospholipids in Drug Toxicity?
Phospholipids are crucial in drug delivery systems and can influence drug toxicity. They are used in the formulation of liposomes, which can encapsulate drugs, reducing their toxicity by altering distribution and metabolism. However, some drugs can cause phospholipidosis, a condition characterized by the accumulation of phospholipids within cells, leading to potential toxicity. This highlights the dual role of phospholipids in both mitigating and contributing to drug toxicity.
