Species differences can impact toxicity in several ways:
1. Metabolic Rate: Species with higher metabolic rates may process toxins more quickly or slowly, affecting the substance's toxicity. 2. Enzyme Activity: Different species may have varying levels of detoxifying enzymes, which can influence how a toxin is metabolized. 3. Organ Sensitivity: Certain organs may be more sensitive to toxins in one species than in another, leading to different clinical manifestations of toxicity. 4. Absorption and Excretion: The efficiency of toxin absorption and excretion can vary, affecting the overall toxicity.
