The 3Rs provide a framework that enhances both ethical and scientific standards in toxicology. By focusing on ethical considerations, researchers can ensure that their work is socially responsible. Moreover, the 3Rs can lead to more innovative research practices, encouraging the development of new technologies and methodologies.
Incorporating the 3Rs also aligns with regulatory changes worldwide. Many countries are adopting stricter regulations regarding animal use in research, and the 3Rs help researchers comply with these requirements, ensuring that their work can be accepted internationally.