3rs (replacement, reduction, refinement)

How Does Reduction Work in Toxicology?

Reduction involves strategies to minimize the number of animals used in experiments without compromising the quality and reliability of the results. This can be achieved through better experimental design, statistical methods, and technologies that enhance data collection efficiency.
One way to practice reduction is by optimizing study designs to ensure that each animal used provides maximum information. Advanced statistical techniques can also help in designing experiments that require fewer animals while still yielding significant results. Moreover, sharing data and resources among researchers can prevent unnecessary repetition of experiments.

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