Replacement refers to the methods that enable researchers to avoid or replace the use of animals in experiments. This can be accomplished by using alternative methods such as in vitro (cell culture) techniques, computer models, or using lower organisms like zebrafish instead of mammals. The goal is to find equivalent or better methods that do not involve animals, thereby reducing ethical concerns.
Why is replacement important? It's not only about ethics but also about scientific advancements. In many cases, alternative methods can offer more precise and human-relevant data. For example, human cell-based assays can provide insights into toxicological responses that are more applicable to humans than those obtained from animals.
