Toxic compounds can interfere with beta oxidation in several ways:
Enzyme Inhibition: Some toxins inhibit enzymes crucial for beta oxidation, such as acyl-CoA dehydrogenase, leading to the accumulation of fatty acids and their derivatives. Mitochondrial Dysfunction: Toxins like carbon tetrachloride can cause mitochondrial damage, impairing the organelle's ability to carry out beta oxidation. Oxidative Stress: Certain toxicants increase reactive oxygen species (ROS) production, which can damage mitochondrial components and inhibit beta oxidation.
