Disruption of beta oxidation can be detected through various diagnostic approaches:
Biochemical Assays: Measurement of fatty acid and acylcarnitine levels in blood or urine can indicate beta oxidation defects. Mitochondrial Function Tests: Assessing mitochondrial enzyme activity and oxygen consumption rates can reveal functional impairments. Genetic Testing: Identifying mutations in genes encoding beta oxidation enzymes can help diagnose inherited metabolic disorders.
