The mechanisms by which toxins cause headaches can vary. Some of the primary mechanisms include:
Vasodilation – Certain toxins can cause the blood vessels in the brain to dilate, leading to a headache. Neurotoxicity – Direct damage to the nervous system by toxic substances can result in headache as a symptom. Inflammation – Some toxins can trigger inflammatory responses in the body, including in the brain, leading to headaches. Hypoxia – Toxins like carbon monoxide reduce oxygen delivery to the brain, causing headaches due to hypoxia.