Diet can significantly impact the absorption, metabolism, and excretion of toxicants. Certain foods can enhance or inhibit the activity of enzymes responsible for metabolizing toxins. For instance, grapefruit contains compounds that inhibit cytochrome P450 enzymes, which can lead to increased blood levels of certain drugs and chemicals, potentially causing toxicity. Conversely, a diet rich in antioxidants found in fruits and vegetables may provide a protective effect by neutralizing free radicals generated by toxin exposure.
