What are the Therapeutic Implications of Targeting DISC?
Targeting DISC has significant therapeutic potential. In cancer therapy, enhancing DISC-mediated apoptosis can selectively kill tumor cells. Conversely, in conditions where excessive apoptosis contributes to disease, such as neurodegenerative disorders, inhibiting DISC may be beneficial. Furthermore, understanding how toxicants influence DISC can lead to the development of strategies to protect normal tissues from toxic damage while maximizing the efficacy of therapeutic interventions.
