How Does FRAP Contribute to Understanding Mechanisms of Toxicity?
By providing quantitative data on molecular mobility, FRAP helps to elucidate the mechanisms by which toxins exert their effects. For instance, alterations in membrane fluidity can be detected through changes in the diffusion rates of fluorescently labeled lipids or proteins. Such alterations might indicate membrane damage or changes in lipid raft organization, which could be critical in understanding the early events in toxin-induced cellular injury.
