The exact mechanism of action for ILE therapy in toxicology is not fully understood, but several hypotheses have been proposed:
- Lipid Sink Theory: This is the most widely accepted theory. It suggests that the lipid emulsion acts as a "sink" that absorbs and sequesters lipophilic toxins in the bloodstream, thereby reducing their availability to target tissues.
- Metabolic Effects: Lipids might enhance the metabolism of the toxic substances, promoting faster clearance from the body.
- Direct Cardiac Effects: The lipids may provide an energy substrate for the heart, especially in cases of cardiotoxicity, thereby improving cardiac output and function.
