Nanotoxicology focuses on the health effects of nanomaterials, where shape plays a significant role. Nanoparticles can vary in shape, including spheres, rods, and sheets, each influencing their biological interactions. For instance, rod-shaped nanoparticles may have a higher likelihood of cellular uptake compared to spherical ones due to their increased surface area. The shape of nanoparticles can also affect their cytotoxicity, biodistribution, and immune response. Thus, the design of safe nanomaterials requires careful consideration of both size and shape.
