In pharmacology, the shape and size of a drug molecule can significantly influence its efficacy and safety. Drug molecules are designed to fit specific targets in the body, much like a lock and key. If a drug's shape is altered, it might fit unintended targets, potentially causing toxic side effects. Similarly, the size of a drug can affect its distribution and clearance from the body. Larger molecules may have prolonged circulation times but could also be more prone to accumulation and toxicity.
