What Role Does Particle Size Play in Inhalation Toxicology?
Inhalation toxicology examines the impact of airborne particles on health. The aerodynamic diameter of particles is critical in determining where they deposit in the respiratory tract. Particles larger than 10 micrometers are typically trapped in the nose or throat, whereas those smaller than 2.5 micrometers (PM2.5) can reach the alveoli in the lungs. Ultrafine particles, like nanoparticles, can even enter the bloodstream. As such, understanding particle size distribution is vital for assessing the risk of respiratory exposure to pollutants.
