How Does Splenectomy Influence Toxicological Research?
In toxicological research, splenectomized animals are often used to study the effects of toxins and drugs in a system with a compromised immune response. This research helps in understanding the role of the spleen in toxicokinetics and toxicodynamics. It also provides insights into potential therapeutic approaches for managing toxin exposure in splenectomized patients.
In conclusion, splenectomy has significant implications in toxicology due to its impact on the immune system and drug metabolism. Understanding these changes is vital for effective clinical management and for conducting accurate toxicological research.
