Management of G-CSF toxicity involves symptomatic treatment of side effects and discontinuation of the drug if severe reactions occur. Bone pain, a common side effect, can often be managed with analgesics such as acetaminophen or NSAIDs. Monitoring of blood counts and spleen size is essential to prevent serious complications. In cases of severe allergic reactions, immediate cessation of G-CSF and administration of antihistamines or corticosteroids may be required.
