How is In Situ Hybridization Applied in Toxicology?
In toxicology, ISH can be used to examine how exposure to various toxicants affects gene expression patterns in different tissues. By providing spatial context, ISH helps researchers understand tissue-specific effects and the molecular mechanisms underlying toxic responses. This technique is especially useful in assessing the impact of toxins on gene expression within specific cell types or regions of interest in organs, such as the liver, brain, or lungs.
