How is the Sigmoidal Curve Applied in Risk Assessment?
In risk assessment, the sigmoidal curve is applied to determine safe exposure levels for humans and the environment. By identifying key points on the curve, such as the NOAEL (No Observed Adverse Effect Level) and the LOAEL (Lowest Observed Adverse Effect Level), regulators can establish guidelines and regulatory limits to protect public health. The curve also aids in the development of dose extrapolation methods, which are used to estimate human risk based on animal study data.
