antagonistic

How to Assess Antagonistic Interactions?

Assessing antagonistic interactions involves various approaches:
Experimental Studies: Laboratory experiments, such as in vitro and in vivo studies, are conducted to observe potential antagonistic effects between substances.
Mathematical Models: Models like the Loewe additivity model or Bliss independence model help predict interactions based on dose-response relationships.
Mechanistic Understanding: A deep understanding of the biochemical pathways involved helps predict and explain antagonistic interactions.

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