Aminoglycoside antibiotics are a class of antibiotics used to treat serious infections caused by bacteria, particularly Gram-negative bacteria. They are derived from Streptomyces species or are synthetically manufactured. Some common examples include gentamicin, tobramycin, and amikacin. These antibiotics work by binding to the bacterial 30S ribosomal subunit, leading to the disruption of protein synthesis which ultimately results in bacterial cell death.